Journal
CLINICAL PEDIATRICS
Volume 41, Issue 5, Pages 309-314Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/000992280204100503
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Care of individuals with renal failure continues to impose a tremendous burden on our national health care budget. Chronic renal failure is the final common denominator of a Multiplicity, of pathologic processes, some of which progress silently over years. Of these, obstructive uropathy is a prominent cause of kidney failure, accounting for 16.5% of all pediatric renal transplants in 1997. The pathophysiology of obstructive uropathy is reviewed as the basis for a differential diagnosis. In view of the significant role played by obstructive uropathy in the development of renal failure, early and definitive treatment of this clinical entity is imperative.
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