4.4 Article

Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus

Journal

INFECTION AND IMMUNITY
Volume 70, Issue 6, Pages 3281-3283

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.70.6.3281-3283.2002

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Funding

  1. NIAID NIH HHS [R01AI24912, P01 AI37194, R01 AI024912, P01 AI037194] Funding Source: Medline
  2. NIDCR NIH HHS [R01 DE011375, R01 DE11375-05A2] Funding Source: Medline

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Previous evaluation of HWP1 in systemic candidiasis in CBA/J mice was done with Candida albicans strains with differing genetic locations of URA3 as a result of Ura-blaster mutagenesis. In this study, the presence of HWP1 and the location of UP,43 contributed to the severity of murine systemic candidiasis in BALB/c mice.

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