4.7 Article

One-pot synthesis of benzo[b]furan and indole inhibitors of tubulin polymerization

Journal

JOURNAL OF MEDICINAL CHEMISTRY
Volume 45, Issue 12, Pages 2670-2673

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jm020077t

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Funding

  1. NCI NIH HHS [N01-CO-1240] Funding Source: Medline

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Benzo[b]furan and indole analogues of some recently identified benzo[b]thiophene inhibitors of tubulin polymerization have been prepared, and their biological activity has been assessed. Several very potent analogues were identified.

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