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Identification of Asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Volume 124, Issue 23, Pages 6544-6545

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AMER CHEMICAL SOC

DOI: 10.1021/ja020214b

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NCI NIH HHS [CA 76461] Funding Source: Medline

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Identification of Asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate

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Identification of Asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Publisher

AMER CHEMICAL SOC

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