Journal
SCIENCE
Volume 296, Issue 5575, Pages 2028-2033Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1071837
Keywords
-
Categories
Funding
- NLM NIH HHS [R01-LM06845] Funding Source: Medline
Ask authors/readers for more resources
Comparison of the whole-genome sequence of Bacillus anthracis isolated from a victim of a recent bioterrorist anthrax attack with a reference reveals 60 new markers that include single nucleotide polymorphisms (SNPs), inserted or deleted sequences, and tandem repeats. Genome comparison detected four high-quality SNPs between the two sequenced B. anthracis chromosomes and seven differences among different preparations of the reference genome. These markers have been tested on a collection of anthrax isolates and were found to divide these samples into distinct families. These results demonstrate that genome-based analysis of microbial pathogens will provide a powerful new tool for investigation of infectious disease outbreaks.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available