4.8 Review

Germline stem cell transplantation and transgenesis

Journal

SCIENCE
Volume 296, Issue 5576, Pages 2174-2176

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1071607

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Funding

  1. NICHD NIH HHS [R01 HD036504] Funding Source: Medline
  2. PHS HHS [36504] Funding Source: Medline

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The recently developed testis cell transplantation method provides a powerful approach to studying the biology of the male germline stem cell and its microenvironment, the stem cell niche. The technique also is being used to examine spermatogenic defects, correct male infertility, and generate transgenic animals.

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