Journal
TRENDS IN CELL BIOLOGY
Volume 12, Issue 7, Pages 299-303Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0962-8924(02)02310-3
Keywords
-
Categories
Ask authors/readers for more resources
Most mitochondrial proteins are nuclear encoded and have to be transported into the organelle after synthesis on cytosolic ribosomes. Three multimeric protein complexes have been identified that import precursor proteins destined for the mitochondria: the TOM complex in the outer membrane and two TIM complexes in the inner membrane. Recent work has provided a detailed view of the different mechanisms operating during the import of the two major classes of mitochondrial proteins - hydrophilic proteins with cleavable presequences and hydrophobic proteins with multiple internal signals.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available