Journal
MICROBES AND INFECTION
Volume 4, Issue 9, Pages 975-981Publisher
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DOI: 10.1016/S1286-4579(02)01624-6
Keywords
Leishmania; lipophosphoglycan; protein kinase C
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The most abundant surface glycoconjugate of the Leishmania promastigotes is lipophosphoglycan, a glycosylphosphatidyl-inositol-anchored polymer of the repeating disaccharide-phosphate Gal(beta1,4)Manalpha1-PO4 unit. This complex molecule possesses properties that contribute to the ability of Leishmania to modulate macrophage signaling pathways during the initiation of infection. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
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