Journal
FERTILITY AND STERILITY
Volume 78, Issue 1, Pages 29-33Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0015-0282(02)03168-0
Keywords
intrauterine insemination; age; pregnancy; spontaneous abortion; live birth
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Objective: To determine how advancing female age decreases successful outcomes of intrauterine insemination (IUI) alone or combined with ovarian stimulation. Design: Retrospective review. Setting: Academic fertility center. Patient(s): Infertile men and women. Intervention(s): Intrauterine insemination alone or combined with ovarian stimulation. Main Outcome Measure(s): Pregnancy rates, miscarriage rates, and live birth rates per insemination cycle according to female age. Result(s): The 1,117 cycles of IUI resulted in 217 pregnancies, for an overall pregnancy rate for all female ages of 19.4% and a live birth rate of 12.9% per cycle inseminated. The overall live birth rate per insemination declined with advancing maternal age. Conclusion(s): Advancing female age decreases successful outcomes with IUI. The live birth rate with IUI for women 40-42 years old (n = 82) was 9.8% per insemination and may demonstrate that IUI is an appropriate treatment for this age group of women. (C) 2002 by American Society for Reproductive Medicine.
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