Journal
JOURNAL OF BACTERIOLOGY
Volume 184, Issue 13, Pages 3740-3745Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.184.13.3740-3745.2002
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Funding
- NIAID NIH HHS [AI42797, R01 AI042797] Funding Source: Medline
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Yersinia enterocolitica organisms secrete Yop proteins via the type III pathway. Translational fusion of yop genes to ubiquitin or dihydrofolate reductase results in hybrid proteins that cannot be secreted. The folding of hybrids prevents their own transport, but it does not hinder the type III secretion of other Yops.
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