Journal
IMMUNITY
Volume 17, Issue 1, Pages 1-6Publisher
CELL PRESS
DOI: 10.1016/S1074-7613(02)00338-2
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The importance of CD8 T cells in the pathogenesis of organ-specific autoimmune diseases has not previously been well recognized. Recent evidence, however, indicates that autoreactive CD8 T cells can contribute substantially to tissue damage in both murine and human autoimmune disorders. As such, these T cells now become an attractive target for therapeutic intervention.
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