Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 3, Issue 7, Pages 509-519Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm858
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Degradomics - the application of genomic and proteomic approaches to identify the protease and protease-substrate repertoires, or 'degradomes', on an organism-wide scale - promises to uncover new roles for proteases in vivo. This knowledge will facilitate the identification of new pharmaceutical targets to treat disease. Here, we review emerging degradomic techniques and concepts.
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