Journal
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
Volume 26, Issue 4, Pages 251-264Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0895-6111(02)00011-3
Keywords
image processing; image segmentation; software; MR imaging; cortical surface
Funding
- NIMH NIH HHS [MH31593, MH40856, MHCRC43271] Funding Source: Medline
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Medical imaging has opened a new door into biomedical research. In order to study various diseases of the brain and detect their impact on brain structure, robust and user friendly image processing packages are required. These packages must be multi-faceted to distinguish variations in size, shape, volume, and the ability to detect longitudinal changes over the course of an illness. This paper describes the BRAINS2 image processing package, which contains both manual and automated tools for structural identification, methods for tissue classification and cortical surface generation. These features are described in detail, as well as the reliability of these procedures. (C) 2002 Elsevier Science Ltd. All rights reserved.
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