Journal
ACCOUNTS OF CHEMICAL RESEARCH
Volume 35, Issue 7, Pages 491-499Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ar010110q
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This Account summarizes techniques for fabrication and applications in biomedicine of microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS). The methods and applications described focus on the exploitation of the physical and chemical properties of PDMS in the fabrication or actuation of the devices. Fabrication of channels in PDMS is simple, and it can be used to incorporate other materials and structures through encapsulation or sealing (built reversible and irreversible).
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