4.7 Article

Prevalence of the fsr locus in Enterococcus faecalis infections

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 40, Issue 7, Pages 2651-2652

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.40.7.2651-2652.2002

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Funding

  1. DRS NIH HHS [RS1/CCR820631] Funding Source: Medline

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The fsr locus of Enterococcus faecalis confers virulence in animal models. A retrospective analysis of fsr prevalence in diverse E. faecalis clinical isolates demonstrated fsr in all endocarditis isolates versus 53% of stool isolates (P = 0.005). This supports a role for fsr-mediated virulence in the pathogenesis of enterococcal infections in humans.

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