Journal
BIOMATERIALS
Volume 23, Issue 13, Pages 2789-2794Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0142-9612(02)00015-7
Keywords
calcium phosphate ceramic; biomaterial; interface; cellulose ether
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Calcium phosphate (CaP) ceramics are the main raw, materials used to elaborate blocks or granules for bone substitutes. In this study injectable bone Substitutes (1BS) were developed for application,, it) orthopedic or dental surgery. Sterile, ready-to-use composite containing CaP granules (biphasic calcium phosphate. BCP) and polymer (hydroxypropylmethylcellulose, HPMC) was prepared. Steam sterilization produced ne. phenomena at the CaP polymer interface. resulting in crystal growth. These phenomena may constitute a model for the biomineralization study. Scanning electron microscopy showed that the formed crystallites organize themselves into a three-dimensional structure. Currently, the mechanisms of crystal growth are unknown and have been observed with only one combination of polymer BCP ceramics after steam sterilization. (C) 2002 Elsevier Science Ltd. All rights reserved.
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