Journal
NATURE REVIEWS CANCER
Volume 2, Issue 7, Pages 514-520Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc841
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Ten years ago, the first melanoma patient was successfully treated by vaccination with a short peptide, which was, in fact, the first tumour-specific T-cell epitope ever defined - MAGE. Since then, a number of clinical vaccination studies have underlined the potential of tumour-specific T-cell epitopes. But, how can we identify more epitopes to improve their efficacy as an anticancer treatment?.
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