Journal
ATHEROSCLEROSIS
Volume 211, Issue 2, Pages 596-600Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.atherosclerosis.2010.02.036
Keywords
Epicardial fat; Obesity; Metabolic syndrome; Children
Ask authors/readers for more resources
Objective: The goal of the study was to assess the association between epicardial fat (EF) thickness and waist circumference, insulin resistance and other metabolic syndrome components in obese children. Methods: 52 obese children (23 males and 29 females) in the mean age 11.6 +/- 2.87 years were studied. Their mean BMI was 26.17 +/- 2.13. Control group included 54 normal weight children (22 males and 32 females) in the mean age 12.85 +/- 2.15 years (BMI -18.55 +/- 2.71). Obesity was defined according to IOTF criteria. EF thickness on the right ventricle was obtained in all children by two-dimensional M-mode echocardiogram. In obese children systolic (SBP) and diastolic (DBP) blood pressure was measured and fasting serum triglycerides, low-and high-density lipoproteins, cholesterol, and glucose and insulin levels were measured. Metabolic syndrome was determined according to IDF 2007 criteria. Results: We documented a statistically significant correlation between epicardial fat BMI z-score and waist circumference in both groups. No statistically significant correlation between EF thickness and HOMA Index was found. There was also no statistically significant difference in EF thickness between obese children with or without metabolic syndrome. Conclusion: Although EF in overweight children is a good indicator of visceral fat it does not seem to be the independent predictor of metabolic syndrome in this age group. The lack of relationship of EF thickness with insulin resistance and metabolic syndrome suggests that in children the prognostic value of this fat tissue may differ from that in adults. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available