4.7 Review

Modern trends in the speciation of selenium by hyphenated techniques

Journal

ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 373, Issue 6, Pages 422-431

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00216-002-1405-9

Keywords

selenium compounds; element-selective detection; hyphenated techniques; HPLC-ICP-MS; (IC)-ICP-MS; GC-AED

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The complexity of selenium speciation in the environment and in living organisms results in broad analytical challenges. The importance of the selective determination of the particular species of this element, to understand its metabolism and biological significance in clinical chemistry, biology, toxicology, and nutrition, calls for state-of-the-art analytical techniques. In this paper hyphenated techniques are evaluated with particular emphasis on interfaced separation with element-selective detection and identification of the selenium compounds detected.

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