Journal
TETRAHEDRON LETTERS
Volume 43, Issue 27, Pages 4841-4844Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)00907-3
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An enantioselective synthesis or (-)-laulimalide is described. Key reactions include a convergent allylation coupling reaction, asymmetric conjugate addition, the allenylstannane Ferrier reaction and a chelation-controlled alkenylzine addition as the basis for stereocontrol in critical elements of chirality. (C) 20021 Elsevier Science Ltd. All rights reserved.
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