Pd(OAc)2/2-aryl-2-oxazolines catalyzed Suzuki coupling reactions of aryl bromides and arylboronic acids

A series of 2-aryl-2-oxazolines were prepared and examined as ligands for the Suzuki coupling reaction of aryl bromides and arylboronic acids. 2,2'-(1,3-Phenylene)bisoxazoline/Pd(OAc)(2) was found to be an efficient catalyst for a variety of substrates to afford the coupling products in good to excellent yields. (C) 2002 Elsevier Science Ltd. All rights reserved.