Highly efficient and practical resolution of 1,1′-spirobiindane-7,7′-diol by inclusion crystallization with N-benzylcinchonidinium chloride

The chiral spirobiindane ligand, 1,1'-spirobiindane-7,7'-diol has been resolved efficiently by inclusion complexation with commercially available N-benzylcinchonidinium chloride. The resolved complex was Studied by X-ray crystallography in order to characterize the intermolecular interactions and recognition nature. (C) 2002 Elsevier Science Ltd. All rights reserved.