4.5 Article

Asymmetric hydroformylation with highly crosslinked polystyrene-supported (R,S)-BINAPHOS-Rh(I) complexes:: The effect of immobilization position

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 12, Issue 14, Pages 1825-1827

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(02)00267-6

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A new class of polymer-supported (R,S)-BINAPHOS 1e in which the parent BINAPHOS has two alkoxy-substituents at the 3-positions of the phenyls, has been synthesised. Using its Rh(I) complex, asymmetric hydroformylation of olefins proceeded with higher enantioselectivity in some cases compared to the conventional polymer-supported 1c. (C) 2002 Elsevier Science Ltd. All rights reserved.

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