Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 12, Issue 4, Pages 403-408Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(02)00317-9
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We review recent work that shows that the iroquois (Iro/Irx) homeobox genes have conserved genomic organization in Drosophila and vertebrates. In addition, these genes play pivotal functions in the initial specification of the vertebrate neuroectoderm, and, in collaboration with other transcription factors, later subdivision of the anterior-posterior and dorso-ventral axis of the neuroectoderm.
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