Journal
JOURNAL OF NATURAL PRODUCTS
Volume 65, Issue 8, Pages 1111-1116Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np020084k
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Eleven new diterpenoids, adenanthins B-L (1-11), together with five known analogues, calcicolin B (12), adenanthin (13), weisiensin A (14), nervosanin (15), and forrestin C (16), were isolated from the aerial parts of Isodon adenantha The structures of 1-11 were elucidated on the basis of spectral methods, as well as the X ray crystallographic analysis of 11 Compounds 2, 5, and 14 showed significant inhibitory activities against K562 cells, with IC50 values less than 4 mug/mL, respectively.
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