Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 14, Issue 4, Pages 509-516Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0952-7915(02)00357-6
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Funding
- NCI NIH HHS [CA71971] Funding Source: Medline
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An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8(+) up T cells. New evidence strongly implicates these 'NK cell receptors' in modulating NK cell and virus-specific CD8(+) T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.
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