Journal
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Volume 53, Issue 5, Pages 1380-1387Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0360-3016(02)02893-6
Keywords
STI; lung tumor; dose distribution; X-ray energy; EGS4
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Purpose: To aid in the selection of incident X-ray energy for stereotactic irradiation (STI) of lung tumor, dose distribution was investigated in a model of a thorax embedded with a tumor. Methods and Materials. The dose distribution in a thorax model was calculated using the EGS4 Monte Carlo simulation; it was also measured with dosimetric film of a tentative thorax phantom. Uniformity of dose distribution in a tumor region was compared among the results of irradiation for several X-ray energies, and optimal X-ray energy for STI of a lung tumor was discussed. Results: Dose distributions in the thorax were obtained. An increase in X-ray energy led not only to an increased dose delivered to the tumor, but also to an increased dose to surrounding normal lung tissue. Conclusions: The flat range in dose distribution along the beam axis and in the beam profiles of the tumor increases with decreasing X-ray energy. Consequently, lower energy, rather than higher energy, is recommended for STI of a lung tumor in terms of higher uniformity in the target volume. (C) 2002 Elsevier Science Inc.
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