4.5 Article Proceedings Paper

Pyrethroid exposure of the general population - is this due to diet?

Journal

TOXICOLOGY LETTERS
Volume 134, Issue 1-3, Pages 141-145

Publisher

ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0378-4274(02)00183-2

Keywords

pyrethroids; urine; biological monitoring; pesticides; general population

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Inhabitants (1177) of a residential area in Frankfurt/Main have been investigated with respect to their internal exposure to pyrethroids. Biological monitoring revealed a body burden of pyrethroids. The 95th percentile for the urinary metabolites of pyrethroids, such as permethrin and cypermethrin, cis and trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid (cis-DCCA and trans-DCCA), was determined to be 0.5 and 1.4 mug/l, respectively. 95th percentile for cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid (DBCA), a specific metabolite of deltamethrin, and 4-fluoro-3-phenoxybenzoic acid (F-PBA), a metabolite of cyfluthrin, were 0.3 and 0.27 mug/l, respectively. The metabolic pattern found for these samples points out that pyrethroids are probably ingested orally with daily diet. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

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