4.4 Article

Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidite complex

Journal

TETRAHEDRON LETTERS
Volume 43, Issue 32, Pages 5541-5544

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)01142-5

Keywords

asymmetric hydrogenation; enamides; rhodium complex; monophos

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The monodentate phosphoramidite ligand monophos was used in the Rh-catalyzed asymmetric hydrogenation of enamides to give high enantioselectivities (up to 96% ee). (C) 2002 Published by Elsevier Science Ltd.

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