Journal
JOURNAL OF CELL BIOLOGY
Volume 158, Issue 3, Pages 401-408Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.200205077
Keywords
bacterial pathogenesis; Yersinia; Yops; translocation; type III secretion
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Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors into cells of the host immune system where they inhibit signaling cascades and block the cells' response to infection. Understanding the molecular mechanisms of this system has provided insight into the processes of phagocytosis and inflammation.
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