Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 242, Issue 1-2, Pages 219-223Publisher
ELSEVIER
DOI: 10.1016/S0378-5173(02)00161-8
Keywords
drug delivery systems; microcapsules; encapsulation; layer-by-layer; biocompatibility; polymers
Categories
Ask authors/readers for more resources
A novel method to include poorly water-soluble substances into the polyelectrolyte, capsules of defined size, stability, composition and affinity properties is proposed. Encapsulation explores the polarity gradient across the capsule wall. Capsules creation makes use of electrostatic interaction and can involve many substances as layer constituents, such as synthetic polyelectrolytes, proteins, nucleic acids, lipids and multivalent dyes. Using capsules made of synthetic polyelectrolytes as a model system was demonstrated how to prepare, to measure and to use this gradient for low molecular weigh materials encapsulation. (C) 2002 Elsevier Science B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available