Journal
JOURNAL OF PHYSICS-CONDENSED MATTER
Volume 14, Issue 33, Pages 7617-7629Publisher
IOP PUBLISHING LTD
DOI: 10.1088/0953-8984/14/33/305
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A simple extension of existing models for protein crystallization is described, in which salt ions and charge neutrality are explicitly incorporated. This provides a straightforward explanation for the shape of protein crystallization boundaries and the associated scaling properties seen for lysozyme, and can also explain much of the salt dependence of the second virial coefficient. The analysis has wider implications for the use of pair potentials in understanding protein crystallization.
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