Journal
MICROBES AND INFECTION
Volume 4, Issue 11, Pages 1149-1156Publisher
EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S1286-4579(02)01640-4
Keywords
gram-positive pathogen; iron; ABC transporter; siderophore
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For the majority of bacterial pathogens, acquisition of iron from host proteins is a prerequisite for growth during infection. The mechanisms by which Gram-negative bacteria obtain iron from host proteins have been well described, but only recently has substantial progress been made in identifying these mechanisms for Gram-positive bacterial pathogens. This review provides an overview of the existing knowledge on the genetic basis of iron transport for important Gram-positive pathogens. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
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