Journal
JOURNAL OF VIROLOGY
Volume 76, Issue 17, Pages 8973-8976Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.76.17.8973-8976.2002
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Funding
- NIAID NIH HHS [AI-2] Funding Source: Medline
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Maturation of vaccinia virus (W) core proteins is required for the production of infectious virions. The W G1L and I7L gene products are the leading candidates for the viral core protein proteinase (vCPP). Using transient-expression assays, data were obtained to demonstrate that the I7L gene product and its encoded cysteine proteinase activity are responsible for vCPP activity.
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