Journal
OPTICS LETTERS
Volume 27, Issue 18, Pages 1610-1612Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.27.001610
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To our knowledge, this is the first demonstration of in vivo depth-resolved birefringence measurements of the human retinal nerve fiber layer (RNFL) by use of polarization-sensitive optical coherence tomography (PS-OCT). Because glaucoma causes nerve fiber layer damage, which may cause loss of retinal birefringence, PS-OCT is a potentially useful technique for the early detection of glaucoma. We built a fiber-based PS-OCT setup that produces quasi-real-time images of the human retina in vivo. Preliminary measurements of a healthy volunteer showed that the double-pass phase retardation per unit depth of the RNFL near the optic nerve head is 39 +/- 6degrees/100 mum. (C) 2002 Optical Society of America.
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