Journal
BIOCHIMIE
Volume 84, Issue 9, Pages 841-848Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S0300-9084(02)01459-1
Keywords
catalytic RNA; phosporothioates; stereochemistry; metal coordination
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This review describes some of the contributions of chemistry to the RNA field with a personal bias towards the phosphorothioate modification and the derivatives at the ribose 2'-position. The usefulness of these modifications is discussed and documented with some examples. (C) 2002 Societe francaise de biochimie et biologie moleculaire/Etditions scientifiques et medicales Elsevier SAS. All rights reserved.
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