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Molecular imaging of cancer with positron emission tomography

Journal

NATURE REVIEWS CANCER
Volume 2, Issue 9, Pages 683-693

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NATURE PUBLISHING GROUP
DOI: 10.1038/nrc882

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The imaging of specific molecular targets that are associated with cancer should allow earlier diagnosis and better management of oncology patients. Positron emission tomography (PET) is a highly sensitive non-invasive technology that is ideally suited for pre-clinical and clinical imaging of cancer biology, in contrast to anatomical approaches. By using radiolabelled tracers, which are injected in non-pharmacological doses, three-dimensional images can be reconstructed by a computer to show the concentration and location(s) of the tracer of interest. PET should become increasingly important in cancer imaging in the next decade.

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