Journal
CELL CYCLE
Volume 1, Issue 5, Pages 312-314Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/cc.1.5.144
Keywords
Spindle formation; Spindle matrix; Microtubules; Mitosis
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Funding
- NSF [MCB0090877]
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A stationary spindle matrix has been proposed on theoretical grounds to help mediate force production at the mitotic spindle. Direct molecular evidence for the existence of such a matrix has the potential to profoundly influence our view of the molecular mechanisms leading to chromosome segregation during mitosis. Three recent papers suggest that the spindle matrix may be more than a theoretical idea.
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