New binary and ternary complexes of fluclaxocillin and amino acids with some transition metals. Synthesis, characterization, and cyclic voltammetric studies

The new binary and ternary complexes of fluclaxocillin (HFluc) and amino acids (HAA) [glycine (HGly) and alanine (HAla)] with Fe(II), Fe(III), Co(II), Ni(II) and Cu(II) ions were prepared and characterized using various spectroscopic methods. According to the elemental analyses, the binary complexes were found to have the general formulas [M(Fluc)(X)(H2O)(x)].yH(2)O and [Fe(Fluc)(Cl)(2)(H2O)(2)].4H(2)O while the ternary complexes had the formulas [M(Fluc)(AA)(Cl)(H2O)(x)].yH(2)O and [Fe(Fluc)(AA)(Cl)(H2O)(x)].yH(2)O where M = Fe(II), Co(II), Ni(II) and Cu(II), X = OAc in the case of Cu(II) and Cl in the case of Fe(II), Co(II) and Ni(II), AA = Gly(-) and Ala(-), x = 2-6 and y = 1-3. IR, magnetic and solid reflectance spectral studies were utilized to infer the structure of the complexes. Thermogravimetric analysis (TGA) was utilized to differentiate between coordinated and hydrated water molecules. The Fluc(-), Gly(-) and Ala molecules are decomposed in a second and subsequent steps. Cyclic voltametric investigations of these complexes were also carried out.