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Chabamide, a novel piperine dimer from stems of Piper chaba

Journal

PLANTA MEDICA
Volume 68, Issue 9, Pages 853-855

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2002-34410

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A novel piperine dimer, named chabamide, was isolated from stems of Piper chaba Hunter and its structure was elucidated on the basis of spectroscopic evidence. Chabamide showed antimalarial activity with an IC50 value of 2.7 mug/ml and antituberculosis activity with the minimum inhibitory concentration (MIC) of 12.5 mug/ml.

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