Journal
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
Volume 10, Issue 5, Pages 521-530Publisher
ELSEVIER SCIENCE INC
DOI: 10.1176/appi.ajgp.10.5.521
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Objective: The authors report results from a 7-year prospective study of depression and mortality in 2,558 Medicare recipients age 65 and older. Methods: This report is based on a secondary data analysis of a randomized controlled trial That evaluated the cost-effectiveness of preventive services for older enrollees in an HMO. Results: Subjects with mild-to-moderate depression at baseline did not have an increased risk of mortality compared with those without significant depression. The 3% of older adults with the most severe depressive syndromes, however, had significant increases in mortality, even after adjusting for demographics, health risk behaviors, and chronic medical disorders. Conclusion: The increase in mortality in this group of older adults was comparable to that in participants with chronic medical disorders such as emphysema or heart disease.
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