Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 27, Issue 9, Pages 467-473Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0968-0004(02)02168-0
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- NIGMS NIH HHS [GM 62521] Funding Source: Medline
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Polyunsaturated fatty acids have crucial roles in membrane biology and signaling processes in most living organisms. However, it is only recently that molecular genetic approaches have allowed detailed studies of the enzymes involved in their synthesis. New evidence has revealed a range of pathways in different organisms. These include a complex sequence for synthesis of docosahexaenoic acid (22:6) in mammals and a polyketide synthase pathway in marine microbes.
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