Journal
JOURNAL OF AFFECTIVE DISORDERS
Volume 71, Issue 1-3, Pages 97-103Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0165-0327(01)00416-5
Keywords
mood disorders; unipolar mania; polarity; lithium; psychosis
Categories
Ask authors/readers for more resources
Background: This study aimed to identify the differences between unipolar mania and classical bipolar disorder. Methods: Patients with at least four manic episodes and at least 4 years of follow-up without any depressive episodes were classified as unipolar mania. This group was compared to other bipolar-I patients defined according to DSM-IV regarding their clinical and socio-demographic variables. Results: The rate for unipolar mania as defined by the study criteria was found to be 16.3% in the whole group of bipolar-I patients. Unipolar manic patients tended to have more psychotic features and be less responsive to lithium prophylaxis compared to other bipolar-I patients. Limitations: Because it was a retrospective study, there may be some minor depressive episodes left unrecorded in the unipolar mania group despite careful and thorough investigation. In addition, even with our fairly strict criteria for the diagnosis of unipolar mania, the possibility of a future depressive episode cannot be excluded. Conclusions: Unipolar mania may be the presentation of a nosologically distinct entity. (C) 2002 Elsevier Science B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available