Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 46, Issue 9, Pages 3050-3053Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.46.9.3050-3053.2002
Keywords
-
Categories
Ask authors/readers for more resources
Two putative proteins (NorMI and NorMII) similar to the multidrug efflux protein NorM of Vibrio parahaemolyticus are encoded by the Brucella melitensis 16 M genome. We show that a drug-hypersusceptible Escherichia coli strain overexpressing NorMI displays increased resistance to norfloxacin, ciprofloxacin, gentamicin, tetraphenylphosphonium ion, acriflavine, and berberine. This elevated resistance was proven to be mediated by an energy-dependent efflux mechanism. NorMI belongs to the multidrug and toxic compound extrusion family and is the first multidrug efflux protein identified in Brucella spp.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available