4.4 Article

Highly enantioselective resolution of terminal epoxides using polymeric catalysts

Journal

TETRAHEDRON LETTERS
Volume 43, Issue 37, Pages 6625-6627

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)01446-6

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Poly-salen-Co(III) complexes were employed in the hydrolytic kinetic resolution (HKR) of terminal epoxides and ee's up to 98% were obtained. In the HKR of epichlorohydrin, the polymeric catalysts can be recovered and modified for recycling. The recovered polymer catalyst shows good activity and selectivity. (C) 2002 Elsevier Science Ltd. All rights reserved.

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