Journal
NEUROLOGY
Volume 59, Issue 5, Pages 749-752Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.59.5.749
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The authors demonstrate the potential for poststroke return of activation in regions normally involved in touch discrimination in a serial, whole-brain fMRI study of a patient with marked sensory loss followed by good recovery. A return of activation in ipsilesional primary and bilateral secondary somatosensory cortices was observed at 3 months after stroke and was maintained at 6 months, indicating a reemergence of activation after the interval of somatosensory recovery. There was little evidence of neural plastic changes early after stroke (2 weeks), when sensory loss was severe.
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