Journal
ORGANIC LETTERS
Volume 4, Issue 19, Pages 3283-3286Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol026517s
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Highly enantioselective hydrolytic kinetic resolutions of esters derived from N-acylated alpha-amino acids proceed rapidly at hydorcarbon/water interfaces in the presence of a proline-derived chiral selector. When performed in tandem with an enantioselective biphasic esterification reaction, esters of 100% enantiomeric excess are obtained.
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