Journal
NEUROLOGY
Volume 59, Issue 6, Pages 917-919Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.59.6.917
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To improve sensitivity of the analysis of axon reflex flare reaction, the authors used a laser Doppler scanner and analyzed flare intensity and size induced by histamine iontophoresis simultaneously at the foot and thigh in patients with small-fiber neuropathy (n = 10) and controls (n = 9). Flare size, but not laser Doppler flux, clearly distinguished patients from controls at both locations (p < 0.01) and may be useful for evaluation of small-fiber neuropathies.
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