Journal
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Volume 1577, Issue 3, Pages 471-475Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0167-4781(02)00477-3
Keywords
globin; heme; hepatitis; lipid hydroperoxide peroxidase; mycloperoxidase
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This study cloned cDNA of human homologue (hSTAP) of rat stellate cell activation-associated protein (rSTAP). hSTAP gene is on chromosome 17q and is composed of four exons. Various types of cells including hepatic stellate cells expressed hSTAP mRNA. Recombinant hSTAP was a heme protein with the activity of peroxidase. hSTAP can be used as a marker of quiescent stellate cells in human liver. (C) 2002 Elsevier Science B.V. All rights reserved.
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