Journal
BRAIN RESEARCH REVIEWS
Volume 40, Issue 1-3, Pages 9-18Publisher
ELSEVIER
DOI: 10.1016/S0165-0173(02)00184-4
Keywords
metabotropic glutamate receptors; locomotion; presynaptic inhibition; Ca2+ oscillations; modulation
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Spinal networks generate the motor pattern underlying locomotion. These are subject to modulatory systems that influence their operation and thereby result in a flexible network organization. In this review, we have summarized the mechanisms by which the different metabotropic glutamate receptor subtypes fine-tune the cellular and synaptic properties and thus underlie intrinsic modulation of the activity of the locomotor network in the lamprey. (C) 2002 Elsevier Science B.V. All rights reserved.
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